Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | CETP | P11597 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827663 | 0.96 | CYP2C9 (0.69) | CYP2C9HPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7823974 | 0.94 | CYP2C9 (0.67) | CYP2C9HPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL14429836 | 0.94 | CYP2C9 (0.67) | CYP2C9HPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7821977 | 0.94 | CYP2C9 (0.67) | CYP2C9HPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7825380 | 0.94 | CYP2C9 (0.67) | CYP2C9HPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7828359 | 0.94 | CYP2C9 (0.67) | CYP2C9HPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7821548 | 0.94 | CYP2C9 (0.67) | CYP2C9HPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7825008 | 0.94 | CYP2C9 (0.67) | CYP2C9HPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7824211 | 0.91 | KMT2A (0.68) | CYP2C9HPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL9532980 | 0.91 | CYP2C9 (0.69) | CYP2C9HPGDKMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |