Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.56 |
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAT2A | P31153 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30317123 | 0.85 | CMA1 (0.47) | HDAC1DRD2DRD3GAAMAT2A | |
| SCHEMBL22574233 | 0.82 | HDAC1 (0.55) | HDAC1DRD2DRD3PKMRAB9A | |
| SCHEMBL22574084 | 0.81 | HDAC1 (0.57) | HDAC1DRD2DRD3PKMRAB9A | |
| SCHEMBL8913255 | 0.80 | HDAC1 (0.67) | HDAC1PKMRAB9AGAA | |
| SCHEMBL28488641 | 0.78 | HDAC1 (0.56) | HDAC1PKMRAB9ASCDGAA | |
| SCHEMBL22574329 | 0.76 | HDAC1 (0.57) | HDAC1PKMRAB9ASCDKDM4E | |
| SCHEMBL12315243 | 0.76 | HDAC1 (0.50) | HDAC1DRD2DRD3RAB9AKDM4E | |
| SCHEMBL7838297 | 0.74 | HDAC1 (0.68) | HDAC1DRD2DRD3PKMRAB9A | |
| SCHEMBL17256661 | 0.73 | KMT2A (0.46) | DRD2RAB9AOPRM1OPRL1GAA | |
| SCHEMBL27342675 | 0.73 | MAPT (0.48) | MAT2AKDM4ECMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719773-B1 | IMIDAZOLIDINONE DERIVATIVE, ACID-ADDITION SALT THEREOF, AND REMEDY FOR SENILE DEMENTIA | KYORIN SEIYAKU KK (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-5789425-A | Imidazolidinone derivatives, their acid adducts and therapeutic drugs for senile dementia | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1998-08-04 | — | — | US | disclosed |
| EP-0719773-A1 | IMIDAZOLIDINONE DERIVATIVE, ACID-ADDITION SALT THEREOF, AND REMEDY FOR SENILE DEMENTIA | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |