Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6161089 | 0.99 | MEN1 (0.38) | AURKAAURKBCHEK1POLBMAPK1 | |
| SCHEMBL6157935 | 0.93 | AURKA (0.38) | AURKAAURKBCHEK1POLBMAPK1 | |
| SCHEMBL7835165 | 0.93 | AURKA (0.36) | AURKACHEK1POLBMAPK1KDM4E | |
| Hydrochloric Acid SCHEMBL7164270 | 0.92 | MEN1 (0.38) | AURKAAURKBCHEK1POLBMAPK1 | |
| Hydrochloric Acid SCHEMBL6159358 | 0.92 | KDM4E (0.37) | MAPK1TP53KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6162784 | 0.92 | AURKA (0.35) | AURKACHEK1POLBMAPK1KDM4E | |
| SCHEMBL6159299 | 0.91 | KMT2A (0.40) | AURKAAURKBCHEK1MAPK1KDM4E | |
| Hydrochloric Acid SCHEMBL6159666 | 0.90 | KMT2A (0.39) | AURKAAURKBCHEK1MAPK1KDM4E | |
| SCHEMBL7858511 | 0.89 | AURKA (0.36) | AURKAAURKBMAPK1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL6158829 | 0.89 | AURKA (0.35) | AURKAAURKBMAPK1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131312-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029403-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2000-05-25 | — | — | WO | disclosed |