Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828309 | 0.86 | KDM4E (0.41) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL22042319 | 0.78 | KDM4E (0.41) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL4786418 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL17818863 | 0.75 | KDM4E (0.43) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL2510265 | 0.75 | KDM4E (0.43) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL12112124 | 0.75 | KDM4E (0.43) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL1305073 | 0.72 | KDM4E (0.41) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL1245752 | 0.72 | KDM4E (0.40) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL109229 | 0.72 | KDM4E (0.52) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL4742262 | 0.71 | KDM4E (0.41) | KDM4EALDH1A1MEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087938-A1 | INHIBITORS OF NEURAMINIDASES | ABBOTT LABORATORIES (US) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999054290-A1 | INHIBITORS OF NEURAMINIDASES | ABBOTT LABORATORIES (US) | 1999-10-28 | — | — | WO | disclosed |