Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.43 |
| ▸ | CMA1 | P23946 | 7/20 | 0.42 |
| ▸ | CTSG | P08311 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9348877 | 0.86 | P2RX7 (0.50) | P2RX7CMA1CTSGGAAKMT2A | |
| Urea SCHEMBL9736500 | 0.83 | P2RX7 (0.47) | P2RX7CMA1CTSGGAAKMT2A | |
| SCHEMBL8918099 | 0.78 | P2RX7 (0.49) | P2RX7CMA1CTSGGAAKMT2A | |
| SCHEMBL11068437 | 0.77 | EPHX2 (0.41) | P2RX7LMNAMIFEPHX2GAA | |
| SCHEMBL8659739 | 0.77 | MEN1 (0.41) | LMNAMIFEPHX2GAAKMT2A | |
| SCHEMBL7838574 | 0.76 | KMT2A (0.58) | CMA1CTSGLMNAKMT2AMEN1 | |
| SCHEMBL6507558 | 0.75 | EPHX2 (0.40) | P2RX7LMNAMIFEPHX2GAA | |
| SCHEMBL6507915 | 0.75 | P2RX7 (0.40) | P2RX7LMNAMIFEPHX2GAA | |
| SCHEMBL6503665 | 0.75 | MIF (0.40) | P2RX7LMNAMIFEPHX2GAA | |
| SCHEMBL6514422 | 0.74 | EPHX2 (0.39) | P2RX7LMNAMIFEPHX2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721944-B1 | IMIDAZOLIDINE DERIVATIVE AND USE THEREOF | SUNTORY LTD (JP) | 2001-01-17 | — | — | EP | disclosed |
| EP-0721944-A1 | IMIDAZOLIDINE DERIVATIVE AND USE THEREOF | SUNTORY LIMITED (JP) | 1996-07-17 | — | — | EP | disclosed |