SCHEMBL7824909

SCHEMBL7824909

O=C(O)C(Cl)=C(Cl)C(Cl)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7824910 1.00 LMNA (0.40) LMNAALDH1A1
SCHEMBL10593414 0.77 LMNA (0.44) LMNAALDH1A1
SCHEMBL8975938 0.77 LMNA (0.44) LMNAALDH1A1
SCHEMBL8975936 0.77 LMNA (0.44) LMNAALDH1A1
Hydrochloric Acid SCHEMBL11257878 0.74 LMNA (0.42) LMNAALDH1A1
SCHEMBL584638 0.71
SCHEMBL4121114 0.69
SCHEMBL19527097 0.69
SCHEMBL21462597 0.68
Hydrochloric Acid SCHEMBL20516467 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed