Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76386 | 0.86 | ALDH1A1 (0.66) | HPGDALDH1A1CYP1A2 | |
| SCHEMBL9124069 | 0.86 | ALDH1A1 (0.66) | HPGDALDH1A1CYP1A2 | |
| SCHEMBL21998909 | 0.86 | ALDH1A1 (0.66) | HPGDALDH1A1CYP1A2 | |
| SCHEMBL7813320 | 0.86 | ALDH1A1 (0.66) | HPGDALDH1A1CYP1A2 | |
| SCHEMBL5215426 | 0.86 | ALDH1A1 (0.66) | HPGDALDH1A1CYP1A2 | |
| SCHEMBL7829195 | 0.86 | ALDH1A1 (0.66) | HPGDALDH1A1CYP1A2 | |
| SCHEMBL11801804 | 0.84 | ALDH1A1 (0.68) | HPGDNPC1RAB9AALDH1A1CYP1A2 | |
| SCHEMBL5445850 | 0.83 | CNR1 (0.65) | HPGDHTTRAB9AALDH1A1MEN1 | |
| SCHEMBL5445709 | 0.83 | ALDH1A1 (0.59) | HPGDHTTNPC1RAB9AALDH1A1 | |
| SCHEMBL27686977 | 0.82 | ALDH1A1 (0.65) | HPGDALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |