Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 5/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.74 |
| ▸ | HTT | P42858 | 3/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11576174 | 0.87 | GAA (1.00) | GAANPSR1LMNASMN1; SMN2HTT | |
| SCHEMBL2538729 | 0.85 | SMN1; SMN2 (1.00) | GAANPSR1LMNASMN1; SMN2HTT | |
| SCHEMBL30512021 | 0.79 | HSD17B10 (1.00) | GAAHSD17B10PTGS1AKR1C3AKR1C2 | |
| SCHEMBL504029 | 0.79 | HSD17B10 (1.00) | GAAHSD17B10PTGS1AKR1C3AKR1C2 | |
| SCHEMBL30049382 | 0.79 | GAA (0.74) | GAANPSR1LMNASMN1; SMN2HTT | |
| SCHEMBL153055 | 0.79 | GAA (0.74) | GAANPSR1LMNASMN1; SMN2HTT | |
| SCHEMBL744543 | 0.77 | HSD17B10 (0.68) | SMN1; SMN2HTTHSD17B10NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2527402 | 0.77 | HSD17B10 (0.97) | GAAHSD17B10PTGS1AKR1C3AKR1C2 | |
| SCHEMBL27952523 | 0.77 | GAA (0.72) | GAANPSR1LMNASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL2530820 | 0.77 | GAA (0.72) | GAANPSR1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |