Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | PAM | P19021 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5873328 | 1.00 | GAA (0.56) | GAAALDH1A1PAMHTTPPARA | |
| SCHEMBL5873326 | 1.00 | GAA (0.56) | GAAALDH1A1PAMHTTPPARA | |
| SCHEMBL950937 | 0.85 | GAA (0.42) | GAAALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL950935 | 0.85 | GAA (0.42) | GAAALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL948029 | 0.85 | CYP1A2 (0.44) | GAALMNAPPARGNFE2L2CYP1A2 | |
| SCHEMBL948030 | 0.85 | CYP1A2 (0.44) | GAALMNAPPARGNFE2L2CYP1A2 | |
| SCHEMBL3676040 | 0.81 | GAA (0.51) | GAAALDH1A1PAMHTTLMNA | |
| SCHEMBL3673142 | 0.81 | GAA (0.51) | GAAALDH1A1PAMHTTLMNA | |
| SCHEMBL3673139 | 0.81 | GAA (0.51) | GAAALDH1A1PAMHTTLMNA | |
| SCHEMBL5872237 | 0.78 | PPARG (0.46) | GAAALDH1A1HTTLMNAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |