SCHEMBL5872237

SCHEMBL5872237

CCCS(=O)(=O)C=Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPARG P37231 9/20 0.46
LMNA P02545 3/20 0.46
NFE2L2 Q16236 2/20 0.46
HTT P42858 2/20 0.42
GAA P10253 2/20 0.41
ALDH1A1 P00352 2/20 0.41
GLA P06280 1/20 0.41
MAPT P10636 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HIF1A Q16665 1/20 0.41
PKM P14618 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5872086 0.89 LMNA (0.52) PPARGLMNANFE2L2HTTGAA
SCHEMBL5872367 0.87 LMNA (0.46) PPARGLMNANFE2L2HTTGAA
SCHEMBL7902156 0.87 LMNA (0.46) PPARGLMNANFE2L2HTTGAA
SCHEMBL12513073 0.86 PPARG (0.50) PPARGLMNANFE2L2HTTGAA
SCHEMBL9985955 0.86 PPARG (0.50) PPARGLMNANFE2L2HTTGAA
SCHEMBL5872294 0.86 PPARG (0.50) PPARGLMNANFE2L2HTTGAA
SCHEMBL5330913 0.84 PSIP1 (0.40) PPARGLMNANFE2L2GAAALDH1A1
SCHEMBL1324308 0.79 PPARG (0.52) PPARGLMNANFE2L2HTTGAA
SCHEMBL1324312 0.79 PPARG (0.52) PPARGLMNANFE2L2HTTGAA
SCHEMBL1324315 0.79 PPARG (0.52) PPARGLMNANFE2L2HTTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116332900-B Olefin compound and synthesis method thereof 华中科技大学 2024-12-06 CN claimed
CN-116332900-A Olefin compound and synthesis method thereof 华中科技大学 2023-06-27 CN claimed
US-6559198-B2 A contact lens comprising a copolymer consisting essentially of from about 25 to about 60 weight percent of a ethylenically unsaturated fluorosulfone ester monomer having the general formula comonomer selected from the group consisting of NOVICKY NICK (CA) 2003-05-06 US claimed
US-20030027886-A1 Fluorocarbon-sulfone hydrophilic contact lenses, optical medical devices and compositions thereof NOVICKY NICK (CA) 2003-02-06 US claimed
EP-0231572-B1 Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof PROGRESSIVE OPTICAL RES LTD (CA) 1994-11-02 EP claimed
US-4748224-A Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof Devou, Maureen J. (CA) 1988-05-31 US claimed
EP-0231572-A2 Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof PROGRESSIVE OPTICAL RESEARCH LTD. (CA) 1987-08-12 EP claimed
CN-116332900-B Olefin compound and synthesis method thereof 华中科技大学 2024-12-06 CN disclosed
CN-116332900-A Olefin compound and synthesis method thereof 华中科技大学 2023-06-27 CN disclosed
US-7098282-B2 Fluorosulfone-silicone hydrogel, RGP contact lenses, optical medical devices and compositions thereof NOVICKY NICK 2006-08-29 US disclosed
US-20050176907-A1 Fluorosulfone-silicone hydrogel, RGP contact lenses, optical medical devices and compositions thereof NOVICKY NICK (CA) 2005-08-11 US disclosed
EP-1455201-A1 Fluorosulfone-silicone hydrogel RGP contact lenses, optical medical devices and compositions thereof Novicky, Nick N. (CA) 2004-09-08 EP disclosed
US-6559198-B2 A contact lens comprising a copolymer consisting essentially of from about 25 to about 60 weight percent of a ethylenically unsaturated fluorosulfone ester monomer having the general formula comonomer selected from the group consisting of NOVICKY NICK (CA) 2003-05-06 US disclosed
EP-0231572-B1 Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof PROGRESSIVE OPTICAL RES LTD (CA) 1994-11-02 EP disclosed
US-5093447-A Contact lenses NOVICKY NICK N (CA) 1992-03-03 US disclosed
US-4948855-A COPOLYMER OF UNSATURATED SILOXANYLALKOXYESTER AND VINYL SILFONE PROGRESSIVE CHEMICAL RESEARCH, LTD. (CA) 1990-08-14 US disclosed
US-4861850-A CONTACT LENSES PROGRESSIVE CHEMICAL RESEARCH, LTD. (CA) 1989-08-29 US disclosed
US-4748224-A Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof Devou, Maureen J. (CA) 1988-05-31 US disclosed
US-4743106-A POLYMER HAVING AN ORGANOSILOXANYLALKOXY ESTER OF (METH)ACRYLIC ACID MONOMER; MACHINING Devou, Maureen J. (CA) 1988-05-10 US disclosed
EP-0231572-A2 Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof PROGRESSIVE OPTICAL RESEARCH LTD. (CA) 1987-08-12 EP disclosed