Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.65 |
| ▸ | RARB | P10826 | 4/20 | 0.62 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL448815 | 0.89 | RARB (0.50) | TP53TSHRPLA2G4BRARB | |
| SCHEMBL5486023 | 0.87 | TP53 (0.53) | TP53TSHRPLA2G4BRARB | |
| SCHEMBL10492948 | 0.84 | NR5A1 (0.53) | — | |
| SCHEMBL1890228 | 0.83 | CNR2 (0.47) | TP53TSHR | |
| SCHEMBL9303812 | 0.83 | PPARD (0.47) | TP53TSHRRARB | |
| SCHEMBL10513794 | 0.82 | NR5A1 (0.56) | TP53TSHR | |
| SCHEMBL503727 | 0.82 | TP53 (0.96) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL736876 | 0.82 | TP53 (0.89) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL10798086 | 0.82 | TP53 (0.89) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL4238919 | 0.81 | CNR2 (0.47) | TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |