Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 14/20 | 0.49 |
| ▸ | CASR | P41180 | 2/20 | 0.35 |
| ▸ | CCKAR | P32238 | 2/20 | 0.35 |
| ▸ | NOTCH1 | P46531 | 2/20 | 0.33 |
| ▸ | NOTCH3 | Q9UM47 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827288 | 0.90 | CCKBR (0.58) | CCKBR | |
| Hydrochloric Acid SCHEMBL9385743 | 0.81 | CCKBR (0.49) | CCKBR | |
| SCHEMBL9368599 | 0.79 | CCKBR (0.57) | CCKBR | |
| SCHEMBL9368725 | 0.78 | CCKBR (0.49) | CCKBRCCKAR | |
| SCHEMBL6045947 | 0.75 | CCKBR (0.55) | CCKBRCCKAR | |
| SCHEMBL4701528 | 0.75 | CCKBR (0.55) | CCKBRCCKAR | |
| SCHEMBL7817950 | 0.74 | CCKBR (0.82) | CCKBR | |
| SCHEMBL7816266 | 0.74 | CCKBR (0.82) | CCKBR | |
| Hydrochloric Acid SCHEMBL7819113 | 0.73 | CCKBR (0.82) | CCKBR | |
| SCHEMBL8774726 | 0.73 | CCKBR (0.55) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652871-B1 | BENZODIAZEPINE DERIVATIVES | MERCK SHARP & DOHME (GB) | 2001-10-17 | — | — | EP | claimed |