SCHEMBL782567

SCHEMBL782567

Clc1nc(-c2ccccc2)cc(-c2ccccc2)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 9/20 1.00
KMT2A Q03164 9/20 1.00
ALDH1A1 P00352 5/20 1.00
HPGD P15428 5/20 1.00
L3MBTL1 Q9Y468 3/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
MAPT P10636 5/20 0.77
KDM4E B2RXH2 4/20 0.77
TDP1 Q9NUW8 2/20 0.77
ADORA2A P29274 2/20 0.60
ADORA1 P30542 2/20 0.60
HSP90AA1 P07900 1/20 0.55
HSP90AB1 P08238 1/20 0.55
AGTR1 P30556 1/20 0.54
TSHR P16473 1/20 0.54
ATM Q13315 1/20 0.54
LMNA P02545 2/20 0.52
GLA P06280 1/20 0.52
NTSR1 P30989 1/20 0.52
RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24212278 0.95 MEN1 (0.91) MEN1KMT2AALDH1A1HPGDL3MBTL1
SCHEMBL16161050 0.95 MEN1 (0.91) MEN1KMT2AALDH1A1HPGDL3MBTL1
SCHEMBL13728744 0.95 MEN1 (0.91) MEN1KMT2AALDH1A1HPGDL3MBTL1
SCHEMBL30939448 0.95 MEN1 (0.91) MEN1KMT2AALDH1A1HPGDL3MBTL1
SCHEMBL10051514 0.95 MEN1 (0.91) MEN1KMT2AALDH1A1HPGDL3MBTL1
SCHEMBL31448341 0.91 MEN1 (0.83) MEN1KMT2AALDH1A1HPGDL3MBTL1
SCHEMBL15395065 0.91 MEN1 (0.83) MEN1KMT2AALDH1A1HPGDL3MBTL1
SCHEMBL15458641 0.89 MEN1 (0.80) MEN1KMT2AALDH1A1HPGDL3MBTL1
SCHEMBL15458659 0.89 MEN1 (0.80) MEN1KMT2AALDH1A1HPGDL3MBTL1
SCHEMBL13172350 0.89 MEN1 (0.80) MEN1KMT2AALDH1A1HPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1551 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050009817-A1 Substituted heteroaryls INSTITUTES FOR PHARMACEUTICAL DISCOVERY, L.L.C. 2005-01-13 US claimed
CN-114763349-B Organic compound, application and preparation method thereof and organic electroluminescent device using same 北京鼎材科技股份有限公司 2026-05-22 CN disclosed
WO-2026105118-A1 COMPOUNDS USABLE AS MODULATORS OF PERK ACTIVITY RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2026-05-21 WO disclosed
EP-4185591-B1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2026-05-13 EP disclosed
CN-122029252-A Organic light-emitting compound and organic electroluminescent device comprising the same 索路思高新材料有限公司 2026-05-12 CN disclosed
US-12628549-B2 Compound for organic optoelectronic device, composition for organic optoelectronic device, organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2026-05-12 US disclosed
EP-4600325-B1 ORGANIC LIGHT-EMITTING COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME SOLUS ADVANCED MATERIALS CO LTD (KR) 2026-04-29 EP disclosed
US-12497389-B2 Organic electroluminescence device and heterocyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2025-12-16 US disclosed
US-20250361207-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2025-11-27 US disclosed
US-20250346806-A1 ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2025-11-13 US disclosed
EP-1618094-B1 SUBSTITUTED HETEROARYLS AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INST FOR PHARM DISCOVERY INC (US) 2007-09-05 EP disclosed
US-20060122223-A1 Substituted amino carboxylic acids THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC 2006-06-08 US disclosed
EP-1622886-A2 SUBSTITUTED AMINO CARBOXYLIC ACIDS AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE-1B The Institutes for Pharmaceutical Discovery, LLC (US) 2006-02-08 EP disclosed
EP-1618094-A1 SUBSTITUTED HETEROARYLS AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES The Institutes for Pharmaceutical Discovery, LLC (US) 2006-01-25 EP disclosed
US-20050009817-A1 Substituted heteroaryls INSTITUTES FOR PHARMACEUTICAL DISCOVERY, L.L.C. 2005-01-13 US disclosed
US-20040266789-A1 Substituted amino carboxylic acids INSTITUTE FOR DIABETES DISCOVERY, L.L.C. 2004-12-30 US disclosed
WO-2004099171-A2 SUBSTITUTED AMINO CARBOXYLIC ACIDS AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE-1B THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) 2004-11-18 WO disclosed
WO-2004099159-A1 SUBSTITUTED HETEROARYLS AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) 2004-11-18 WO disclosed
US-6706215-B1 2-(2'-HYDROXYPHENYL)-1,3-PYRIMIDINE DERIVATIVE CIBA SPECIALTY CHEMICALS CORPORATION 2004-03-16 US disclosed
US-5753729-A COATING COMPOSITION COMPRISING ORGANIC POLYMER BINDER, 2-(2*-HYDROXYPHENYL)PYRIMIDINE STABILIZER CIBA SPECIALTY CHEMICALS CORPORATION 1998-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12628549-B2 Compound for organic optoelectronic device, composition for organic optoelectronic device, organic optoelectronic device and display device OXER1, C1R, CHRM1 MEN1 1348/4885KMT2A 3233/4885ALDH1A1 1305/4885
US-20050009817-A1 Substituted heteroaryls PTPRS, PTPRO, PTPRR MEN1 2658/4885KMT2A 2730/4885ALDH1A1 477/4885
US-20060122223-A1 Substituted amino carboxylic acids PTPRS, PTPRO, PTPRJ MEN1 3043/4885KMT2A 2273/4885ALDH1A1 343/4885
US-12497389-B2 Organic electroluminescence device and heterocyclic compound for organic electroluminescence device OCIAD1, OCIAD2, SLC25A21 MEN1 2665/4885KMT2A 2123/4885ALDH1A1 1216/4885
US-20250346806-A1 ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME SOD1, L1CAM, ELAVL1 MEN1 2850/4885KMT2A 2553/4885ALDH1A1 385/4885
US-20040266789-A1 Substituted amino carboxylic acids PTPRS, PPM1B, PTPRO MEN1 2140/4885KMT2A 2369/4885ALDH1A1 262/4885
US-20250361207-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, NR2E3, ORC3 MEN1 1847/4885KMT2A 3045/4885ALDH1A1 3702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.