Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826334 | 0.83 | PARP1 (0.60) | TYMS | |
| SCHEMBL27555186 | 0.81 | TYMS (0.58) | TYMS | |
| SCHEMBL22233998 | 0.74 | TYMS (0.56) | TYMS | |
| SCHEMBL6651315 | 0.74 | TYMS (1.00) | TYMS | |
| SCHEMBL14080068 | 0.73 | TYMS (0.70) | TYMS | |
| SCHEMBL6650317 | 0.73 | TYMS (1.00) | TYMS | |
| SCHEMBL6649537 | 0.73 | TYMS (1.00) | TYMS | |
| SCHEMBL6653074 | 0.72 | TYMS (1.00) | TYMS | |
| SCHEMBL6652802 | 0.72 | TYMS (1.00) | TYMS | |
| SCHEMBL6455624 | 0.72 | TYMS (1.00) | TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1335307-A | Synthesis process of 2-amino quinbolone compounds | MILITARY MEDICAL UNIV NO 1 PLA (CN) | 2002-02-13 | — | — | CN | disclosed |
| EP-0637300-B1 | ANTIPROLIFERATIVE QUINAZOLINES | AGOURON PHARMA (US) | 2001-09-05 | — | — | EP | disclosed |
| EP-0637300-A1 | ANTIPROLIFERATIVE QUINAZOLINES | AGOURON PHARMACEUTICALS, INC. (US) | 1995-02-08 | — | — | EP | disclosed |
| WO-1993020055-A1 | ANTIPROLIFERATIVE QUINAZOLINES | AGOURON PHARMACEUTICALS, INC. (US) | 1993-10-14 | — | — | WO | disclosed |