Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.66 |
| ▸ | FAP | Q12884 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | ALB | P02768 | 1/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.56 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.55 |
| ▸ | APEX1 | P27695 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825976 | 1.00 | PTGS1 (0.66) | PTGS1FAPMAPTALDH1A1USP2 | |
| SCHEMBL7815030 | 0.99 | PTGS1 (0.65) | PTGS1FAPMAPTALDH1A1USP2 | |
| SCHEMBL7815032 | 0.99 | PTGS1 (0.65) | PTGS1FAPMAPTALDH1A1USP2 | |
| SCHEMBL7815849 | 0.99 | PTGS1 (0.66) | PTGS1FAPMAPTALDH1A1USP2 | |
| SCHEMBL7815846 | 0.99 | PTGS1 (0.66) | PTGS1FAPMAPTALDH1A1USP2 | |
| SCHEMBL7812937 | 0.91 | FAP (0.77) | PTGS1FAPMAPTALDH1A1USP2 | |
| SCHEMBL7812935 | 0.91 | FAP (0.77) | PTGS1FAPMAPTALDH1A1USP2 | |
| SCHEMBL7826112 | 0.91 | PTGS1 (0.69) | PTGS1FAPMAPTALDH1A1USP2 | |
| SCHEMBL10911611 | 0.91 | PTGS1 (0.73) | PTGS1FAPMAPTALDH1A1USP2 | |
| SCHEMBL10911610 | 0.91 | PTGS1 (0.73) | PTGS1FAPMAPTALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074554-A2 | 7-acyl-3-(substituted carbamoyloxy) cephem compounds, use thereof and process for their preparation | Eisai Co., Ltd. (JP) | 2001-02-07 | — | — | EP | disclosed |
| EP-1074553-A1 | 7-Acyl-3-(substituted carbamoyloxy) cephem compounds, use thereof and process for their preparation | Eisai Co., Ltd. (JP) | 2001-02-07 | — | — | EP | disclosed |
| EP-0761671-A1 | Cephem derivatives | Eisai Co., Ltd. (JP) | 1997-03-12 | — | — | EP | disclosed |
| US-5604217-A | CEPHALOSPORIN ANTIBIOTICS | EISAI CO., LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| US-5587473-A | BLOCKING; CONDENSATION; DEBLOCKING | EISAI CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5563265-A | BACTERICIDES | EISAI CO., LTD. (JP) | 1996-10-08 | — | — | US | disclosed |
| US-5559225-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |