Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083309 | 0.81 | SRC (0.57) | USP2CYP2C9CYP2C19SRCALOX15 | |
| SCHEMBL28082922 | 0.79 | CYP2C9 (0.46) | CYP2C9CYP2C19SRCMEN1KMT2A | |
| SCHEMBL28806215 | 0.76 | CETP (0.44) | CYP2C9CYP2C19SRC | |
| SCHEMBL8759593 | 0.76 | SLC6A4 (0.46) | — | |
| SCHEMBL3401427 | 0.76 | SRC (0.60) | USP2CYP2C9CYP2C19SRCTSHR | |
| SCHEMBL3490037 | 0.76 | SRC (0.54) | CYP2C9CYP2C19SRCTSHRTDP1 | |
| SCHEMBL10529826 | 0.75 | CYP2C19 (0.42) | CYP2C9CYP2C19SRCALOX15MEN1 | |
| Hydrochloric Acid SCHEMBL3065842 | 0.74 | SRC (0.52) | CYP2C9CYP2C19SRCTSHRTDP1 | |
| SCHEMBL30451960 | 0.72 | SRC (0.50) | CYP2C9CYP2C19SRCTSHRTDP1 | |
| Methyl Alcohol SCHEMBL29038483 | 0.72 | SRC (0.50) | CYP2C9CYP2C19SRCTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082313-A1 | BICYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999020614-A1 | BICYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-04-29 | — | — | WO | disclosed |