Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 3/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7459825 | 0.99 | CHRM5 (0.44) | CHRM5CHRM3CHRM1POLBOPRL1 | |
| SCHEMBL7826654 | 0.95 | CHRM5 (0.43) | CHRM5CHRM3CHRM1POLBOPRL1 | |
| Hydrochloric Acid SCHEMBL7461437 | 0.94 | CHRM5 (0.42) | CHRM5CHRM3CHRM1POLBOPRL1 | |
| SCHEMBL7827057 | 0.93 | CHRM5 (0.42) | CHRM5CHRM3CHRM1POLBOPRL1 | |
| Hydrochloric Acid SCHEMBL7469274 | 0.93 | CHRM5 (0.42) | CHRM5CHRM3CHRM1POLBOPRL1 | |
| Hydrochloric Acid SCHEMBL7831909 | 0.90 | CHRM5 (0.46) | CHRM5CHRM3CHRM1POLBOPRL1 | |
| Hydrochloric Acid SCHEMBL7466672 | 0.89 | CHRM5 (0.44) | CHRM5CHRM3CHRM1POLBOPRL1 | |
| Hydrochloric Acid SCHEMBL7460659 | 0.84 | CHRM5 (0.43) | CHRM5CHRM3CHRM1POLBOPRL1 | |
| SCHEMBL7822686 | 0.83 | CHRM5 (0.43) | CHRM5CHRM3CHRM1POLBOPRL1 | |
| Hydrochloric Acid SCHEMBL7458674 | 0.82 | CHRM5 (0.43) | CHRM5CHRM3CHRM1POLBOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712845-B1 | Amine compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-10-17 | — | — | EP | claimed |
| EP-0712845-A1 | Amine compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-22 | — | — | EP | claimed |
| EP-0712845-B1 | Amine compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-5633248-A | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS, DIARYLALKYLIDENEDIAMINES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| EP-0712845-A1 | Amine compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-22 | — | — | EP | disclosed |