Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | EDNRB | P24530 | 6/20 | 0.44 |
| ▸ | EDNRA | P25101 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829208 | 0.97 | ALDH1A1 (0.51) | ALDH1A1HTTL3MBTL1NPC1HSP90AA1 | |
| SCHEMBL7825131 | 0.93 | ALDH1A1 (0.46) | ALDH1A1HTTL3MBTL1NPC1HSP90AA1 | |
| SCHEMBL7831437 | 0.89 | HCRTR2 (0.49) | ALDH1A1HTTL3MBTL1EDNRBEDNRA | |
| SCHEMBL7831616 | 0.89 | EDNRB (0.49) | ALDH1A1HTTL3MBTL1EDNRBEDNRA | |
| SCHEMBL7831152 | 0.87 | EDNRB (0.45) | ALDH1A1HTTL3MBTL1EDNRBEDNRA | |
| SCHEMBL7069237 | 0.86 | ALDH1A1 (0.51) | ALDH1A1HTTL3MBTL1NPC1HSP90AA1 | |
| SCHEMBL7071205 | 0.86 | ALDH1A1 (0.51) | ALDH1A1HTTL3MBTL1NPC1HSP90AA1 | |
| SCHEMBL7827165 | 0.86 | SLC16A3 (0.44) | ALDH1A1HTTL3MBTL1NPC1HSP90AA1 | |
| SCHEMBL7825784 | 0.85 | ALDH1A1 (0.47) | ALDH1A1HTTL3MBTL1EDNRBEDNRA | |
| SCHEMBL7817363 | 0.85 | EDNRA (0.46) | ALDH1A1HTTL3MBTL1EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811001-B1 | BENZOTHIAZINE DIOXIDES AS ENDOTHELIN ANTAGONISTS | WARNER LAMBERT CO (US) | 2001-10-31 | — | — | EP | claimed |