Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 4/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | ATIC | P31939 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826363 | 0.88 | SLC9A1 (0.47) | SLC9A1 | |
| SCHEMBL7830020 | 0.85 | SLC9A1 (0.40) | SLC9A1CYP2D6CYP2C9CYP2C19 | |
| Guanidine SCHEMBL8703294 | 0.78 | CA12 (0.34) | KAT6AHRH3CA12CA1CA2 | |
| SCHEMBL8703297 | 0.77 | KAT6A (0.37) | SLC9A1KAT6AHRH3MEN1KMT2A | |
| SCHEMBL8444457 | 0.77 | DHODH (0.40) | SLC9A1CA12CA1CA2CA9 | |
| SCHEMBL7816491 | 0.76 | KDM4E (0.39) | SLC9A1ATICMEN1KMT2AKDM4E | |
| SCHEMBL7816360 | 0.76 | SLC9A1 (0.34) | SLC9A1KAT6ACA12CA1CA2 | |
| SCHEMBL7830864 | 0.76 | SLC9A1 (0.34) | SLC9A1CA12CA1CA2CA9 | |
| SCHEMBL7825281 | 0.76 | PLAU (0.43) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL7822730 | 0.75 | SLC9A1 (0.46) | SLC9A1KAT6ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699185-B1 | GUANIDINE DERIVATIVES AS INHIBITORS OF Na+ /H+ EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| WO-1994026709-A1 | GUANIDINE DERIVATIVES AS INHIBITORS OF Na+/H+ EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-24 | — | — | WO | disclosed |