SCHEMBL7826474

SCHEMBL7826474

CCCCCCCCOc1ccc2c(c1)C(=N)NC2(OCC)OCC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.40
PTPN1 P18031 1/20 0.40
NR5A1 Q13285 1/20 0.39
TSHR P16473 2/20 0.39
MAPT P10636 2/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39
RAB9A P51151 1/20 0.39
KMT2A Q03164 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PTPN11 Q06124 2/20 0.38
HTR1A P08908 6/20 0.37
HTR1D P28221 6/20 0.37
HTR1B P28222 6/20 0.37
TP53 P04637 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7827424 1.00 PDK2 (0.40) PDK2PTPN1NR5A1TSHRMAPT
SCHEMBL7815934 0.96 MEN1 (0.41) PDK2PTPN1MAPTMEN1NPC1
SCHEMBL7827484 0.91 PDK2 (0.37) PDK2PTPN1MAPTMEN1NPC1
SCHEMBL7827212 0.90 PDK2 (0.46) PDK2PTPN1NR5A1TSHRMAPT
SCHEMBL7825985 0.90 PDK2 (0.46) PDK2PTPN1NR5A1TSHRMAPT
SCHEMBL7827204 0.90 PDK2 (0.42) PDK2PTPN1NR5A1TSHRMAPT
SCHEMBL7830530 0.90 PDK2 (0.42) PDK2PTPN1NR5A1TSHRMAPT
SCHEMBL7816180 0.87 ALDH1A1 (0.43) PDK2TSHRMAPTMEN1NPC1
SCHEMBL7817014 0.86 PDK2 (0.42) PDK2PTPN1MAPTMEN1NPC1
SCHEMBL7830753 0.85 MEN1 (0.40) PDK2PTPN1NR5A1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679640-B1 Carboxylate and heat-sensitive recording material using same MITSUI CHEMICALS INC (JP) 2001-08-08 EP disclosed
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed