Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.64 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.64 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9010378 | 0.88 | AGTR1 (0.59) | AGTR1AGTR2GP6 | |
| SCHEMBL965839 | 0.87 | AGTR1 (0.67) | AGTR1AGTR2GP6 | |
| SCHEMBL18003201 | 0.87 | AGTR1 (0.61) | AGTR1AGTR2GP6 | |
| SCHEMBL9010382 | 0.84 | AGTR1 (0.60) | AGTR1AGTR2GP6 | |
| SCHEMBL8568897 | 0.84 | AGTR1 (0.59) | AGTR1AGTR2GP6 | |
| SCHEMBL28517678 | 0.84 | AGTR1 (0.59) | AGTR1AGTR2GP6 | |
| SCHEMBL4639444 | 0.84 | AGTR1 (0.59) | AGTR1AGTR2GP6 | |
| SCHEMBL9152560 | 0.84 | AGTR1 (0.62) | AGTR1AGTR2GP6 | |
| SCHEMBL3872329 | 0.84 | AGTR1 (0.59) | AGTR1AGTR2GP6 | |
| SCHEMBL3324054 | 0.83 | AGTR1 (0.59) | AGTR1AGTR2GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513533-B1 | Heterocyclic substituted phenylacetic-acid derivatives, process for their preparation and their pharmaceutical application | BAYER AG (DE) | 2001-11-21 | — | — | EP | disclosed |
| EP-1127880-A2 | Phenylacetic acid derivatives substituted by a heterocycle and their use as A-II antagonists and as inhibitors of smooth muscle cell proliferation | BAYER AG (DE) | 2001-08-29 | — | — | EP | disclosed |
| US-5521206-A | HYPOTENSIVE AGENTS, TREATMENT OF ATHEROSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-05-28 | — | — | US | disclosed |
| EP-0513533-A2 | Heterocyclic substituted phenylacetic-acid derivatives, process for their preparation and their pharmaceutical application | BAYER AG (DE) | 1992-11-19 | — | — | EP | disclosed |