Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MITF | O75030 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10726878 | 0.92 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2MITFNPC1RECQL | |
| SCHEMBL29118618 | 0.85 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MITFNPC1RECQL | |
| SCHEMBL1176806 | 0.82 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2MITFNPC1RECQL | |
| SCHEMBL11152089 | 0.82 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MITFNPC1RECQL | |
| SCHEMBL25379723 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2NPC1HSD17B10RAB9A | |
| SCHEMBL31581362 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2NPC1HSD17B10RAB9A | |
| SCHEMBL25380338 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2NPC1HSD17B10RAB9A | |
| SCHEMBL29201220 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2NPC1HSD17B10RAB9A | |
| SCHEMBL25380339 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2NPC1HSD17B10RAB9A | |
| SCHEMBL29153995 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2NPC1HSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| EP-0244175-A2 | Furo (3,4-d) pyrimidine-2, 4-dione derivatives and intermediates thereof | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-11-04 | — | — | EP | disclosed |
| US-4703120-A | VASODILATORS, HYPOTENSIVE AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-10-27 | — | — | US | disclosed |