Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873611 | 0.84 | DPP4 (0.57) | DPP4 | |
| SCHEMBL873610 | 0.84 | DPP4 (0.57) | DPP4 | |
| SCHEMBL7824246 | 0.77 | GRIN2B (0.46) | CCR3GRIN2B | |
| SCHEMBL7813331 | 0.74 | CCR3 (0.64) | CCR3 | |
| SCHEMBL4966754 | 0.74 | GBA1 (0.50) | CCR3GRIN2B | |
| SCHEMBL5999857 | 0.73 | MEN1 (0.64) | MEN1KMT2ACCR3GRIN2B | |
| SCHEMBL590923 | 0.73 | CA1 (0.62) | DPP4 | |
| SCHEMBL28045116 | 0.73 | CA1 (0.62) | DPP4 | |
| SCHEMBL2925616 | 0.72 | MEN1 (0.60) | MEN1KMT2A | |
| SCHEMBL3314580 | 0.71 | DPP4 (0.53) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140834-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Du Pont Pharmaceuticals Company (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000035877-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-06-22 | — | — | WO | claimed |