Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | EGFR | P00533 | 2/20 | 0.61 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.61 |
| ▸ | LTA4H | P09960 | 2/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3806017 | 0.93 | MEN1 (0.73) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL18660195 | 0.91 | MAPT (0.74) | MAPTALDH1A1HPGDGAAEGFR | |
| SCHEMBL19353947 | 0.89 | L3MBTL1 (0.77) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL6766490 | 0.89 | L3MBTL1 (0.77) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL1060805 | 0.89 | HDAC4 (0.73) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL7107371 | 0.89 | POLB (0.82) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL1064861 | 0.87 | HDAC4 (0.77) | MAPTMEN1KMT2AL3MBTL1EGFR | |
| SCHEMBL312344 | 0.87 | HDAC4 (0.77) | MAPTMEN1KMT2AL3MBTL1EGFR | |
| SCHEMBL12112926 | 0.87 | MAPT (0.79) | MAPTALDH1A1POLBHPGDL3MBTL1 | |
| SCHEMBL6296181 | 0.87 | HDAC4 (0.75) | MAPTL3MBTL1GAAEGFRLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |