Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101212 | 0.92 | PTPRC (0.44) | ALDH1A1PTPRCMAPTHTTKMT2A | |
| SCHEMBL7100834 | 0.76 | ALDH1A1 (0.45) | ALDH1A1RAB9AMAPTHTTKMT2A | |
| SCHEMBL7100881 | 0.74 | ALDH1A1 (0.41) | ALDH1A1RAB9AMAPTHTTKMT2A | |
| SCHEMBL7100864 | 0.70 | MAPT (0.39) | ALDH1A1RAB9AMAPTHTTKMT2A | |
| SCHEMBL7100873 | 0.70 | MAPT (0.39) | ALDH1A1RAB9AMAPTHTTKMT2A | |
| SCHEMBL54610 | 0.69 | ALDH1A1 (1.00) | ALDH1A1MAOBRAB9AMAPTHTT | |
| SCHEMBL30780024 | 0.69 | ALDH1A1 (1.00) | ALDH1A1MAOBRAB9AMAPTHTT | |
| SCHEMBL7100452 | 0.68 | KMT2A (0.44) | ALDH1A1RAB9AMAPTHTTKMT2A | |
| SCHEMBL28042240 | 0.68 | ALDH1A1 (0.96) | ALDH1A1MAOBRAB9AMAPTHTT | |
| Hydrochloric Acid SCHEMBL27577695 | 0.68 | ALDH1A1 (0.96) | ALDH1A1MAOBRAB9AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102754-A1 | IMIDAZOLES AND RELATED COMPOUNDS AS ALPHA-1A AGONISTS | ABBOTT LABORATORIES (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000007997-A1 | IMIDAZOLES AND RELATED COMPOUNDS AS α1A AGONISTS | ABBOTT LABORATORIES (US) | 2000-02-17 | — | — | WO | disclosed |