Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 10/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16334610 | 0.86 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTMAOBGAA | |
| SCHEMBL9093546 | 0.86 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTMAOBGAA | |
| SCHEMBL10610370 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTMAOBGAA | |
| SCHEMBL16340262 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTMAOBGAA | |
| SCHEMBL10403858 | 0.80 | ALDH1A1 (0.66) | ALDH1A1KDM4EMAPTMAOBGAA | |
| SCHEMBL6559398 | 0.80 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTMAOBGAA | |
| SCHEMBL29920860 | 0.80 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTMAOBGAA | |
| SCHEMBL10402359 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTMAOBGAA | |
| SCHEMBL10403004 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTMAOBGAA | |
| SCHEMBL4728857 | 0.79 | KDM4E (0.69) | ALDH1A1KDM4EMAPTMAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |