Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.69 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.69 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.69 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.69 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.69 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.69 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 2/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3381070 | 1.00 | HDAC8 (0.69) | HDAC8HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL6138764 | 0.98 | HDAC1 (0.66) | HDAC8HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL3380464 | 0.95 | HDAC8 (0.71) | HDAC8HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL100781 | 0.94 | HDAC1 (0.61) | HDAC8HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL133319 | 0.90 | HDAC1 (0.75) | HDAC8HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL7741993 | 0.86 | HDAC8 (0.71) | HDAC8HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL100952 | 0.86 | NR4A2 (0.65) | HDAC8HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL7907717 | 0.83 | HSD17B3 (0.71) | HDAC8HDAC1HDAC3HDAC2 | |
| SCHEMBL19253754 | 0.83 | HDAC8 (0.67) | HDAC8HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL7789360 | 0.83 | HSD17B3 (0.71) | HDAC8HDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |