Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | P4HB | P07237 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL226720 | 0.83 | KDM4E (0.71) | KDM4ELMNAHSD17B10P4HBGAA | |
| SCHEMBL30574898 | 0.83 | KDM4E (0.71) | KDM4ELMNAHSD17B10P4HBGAA | |
| Water SCHEMBL4310345 | 0.81 | KDM4E (0.69) | KDM4ELMNAHSD17B10P4HBGAA | |
| SCHEMBL2649763 | 0.73 | KDM4E (0.59) | KDM4ELMNAHSD17B10P4HBGAA | |
| SCHEMBL3684976 | 0.73 | ACE2 (0.51) | KDM4ELMNAHSD17B10GAAPTGS2 | |
| SCHEMBL3468841 | 0.73 | KDM4E (0.68) | KDM4ELMNAHSD17B10P4HBGAA | |
| SCHEMBL4609777 | 0.73 | KDM4E (0.69) | KDM4ELMNAHSD17B10P4HBGAA | |
| SCHEMBL9068206 | 0.73 | KDM4E (0.55) | KDM4ELMNAHSD17B10GAAPTGS2 | |
| SCHEMBL32257493 | 0.72 | CA6 (0.64) | KDM4ELMNAHSD17B10GAAPTGS2 | |
| SCHEMBL383555 | 0.72 | CA6 (0.64) | KDM4ELMNAHSD17B10GAAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |