Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828440 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4EPDE7APDE3A | |
| SCHEMBL2637459 | 0.89 | ALDH1A1 (0.72) | ALDH1A1MAPTKDM4EPDE7APDE3A | |
| SCHEMBL3327075 | 0.78 | PDE7A (0.57) | ALDH1A1MAPTKDM4EPDE7APDE3A | |
| SCHEMBL6463568 | 0.78 | PDE7A (0.57) | ALDH1A1MAPTKDM4EPDE7APDE3A | |
| SCHEMBL14991099 | 0.75 | ALDH1A1 (0.66) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL2636854 | 0.74 | ALDH1A1 (0.68) | ALDH1A1MAPTKDM4EPDE7AKMT2A | |
| SCHEMBL3326891 | 0.73 | PDE7A (0.48) | ALDH1A1MAPTKDM4EPDE7APDE3A | |
| SCHEMBL3360701 | 0.72 | ALDH1A1 (0.62) | ALDH1A1MAPTKDM4EPDE7APDE3A | |
| Hydrochloric Acid SCHEMBL3329155 | 0.72 | PDE7A (0.48) | ALDH1A1MAPTKDM4EPDE7APDE3A | |
| SCHEMBL13990244 | 0.71 | TSHR (0.53) | ALDH1A1MAPTKDM4EPDE7APDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |