Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 12/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | USP2 | O75604 | 5/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483434 | 0.83 | BTK (0.43) | CYP3A4KDM4EIRAK4 | |
| SCHEMBL8483437 | 0.83 | BTK (0.43) | CYP3A4KDM4EIRAK4 | |
| SCHEMBL8490025 | 0.83 | IRAK4 (0.45) | CYP3A4KDM4EIRAK4 | |
| SCHEMBL8487365 | 0.83 | BTK (0.42) | KDM4EIRAK4 | |
| SCHEMBL8486785 | 0.83 | BTK (0.42) | KDM4EIRAK4 | |
| SCHEMBL8490115 | 0.82 | BTK (0.42) | CYP1A2CYP2D6MEN1CYP3A4KDM4E | |
| SCHEMBL8582006 | 0.82 | IRAK4 (0.38) | CYP1A2CYP2D6CYP2C19CLK4CYP3A4 | |
| SCHEMBL8581999 | 0.82 | IRAK4 (0.38) | CYP1A2CYP2D6CYP2C19CLK4CYP3A4 | |
| SCHEMBL7198151 | 0.81 | IRAK4 (0.37) | CYP1A2CLK4MEN1CYP3A4HSD17B10 | |
| SCHEMBL8120612 | 0.81 | IRAK4 (0.37) | CYP1A2CLK4MEN1CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300333-B1 | COMPOUNDS AS FUNGICIDES, MITICIDES OR INSECTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 2001-10-09 | — | — | US | disclosed |
| EP-1068197-A1 | SUBSTITUTED PIPERIDINES, METHOD FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES AND FUNGICIDES | Aventis CropScience GmbH (DE) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999051589-A1 | SUBSTITUTED PIPERIDINES, METHOD FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES AND FUNGICIDES | AVENTIS CROPSCIENCE GMBH (DE) | 1999-10-14 | — | — | WO | disclosed |