Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 4/20 | 0.44 |
| ▸ | SLC5A2 | P31639 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5515342 | 0.95 | SLC5A1 (0.45) | SLC5A1SLC5A2POLBMAPTALDH1A1 | |
| SCHEMBL7827659 | 0.94 | SLC5A1 (0.43) | SLC5A1SLC5A2POLBMAPTALDH1A1 | |
| SCHEMBL8057419 | 0.93 | SLC5A1 (0.40) | SLC5A1SLC5A2POLBMAPTALDH1A1 | |
| SCHEMBL8069350 | 0.91 | SLC5A1 (0.44) | SLC5A1SLC5A2POLBMAPTALDH1A1 | |
| SCHEMBL5516696 | 0.91 | SLC5A1 (0.44) | SLC5A1SLC5A2POLBMAPTALDH1A1 | |
| SCHEMBL8067119 | 0.90 | SLC5A1 (0.43) | SLC5A1SLC5A2POLBMAPTALDH1A1 | |
| SCHEMBL7831857 | 0.88 | SLC5A1 (0.43) | SLC5A1SLC5A2POLBMAPTALDH1A1 | |
| SCHEMBL7826196 | 0.88 | SLC5A1 (0.43) | SLC5A1SLC5A2POLBMAPTALDH1A1 | |
| SCHEMBL8071924 | 0.87 | CYP19A1 (0.48) | SLC5A1SLC5A2POLBMAPTALDH1A1 | |
| SCHEMBL7827679 | 0.87 | UCHL1 (0.40) | SLC5A1SLC5A2POLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-5840895-A | INTERMEDIATES FOR ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5686442-A | ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |