Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816217 | 0.91 | GPR35 (0.47) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL7817267 | 0.87 | GPR35 (0.46) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL8341921 | 0.84 | GPR35 (0.46) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL8342857 | 0.83 | GAA (0.50) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL8800071 | 0.81 | GPR35 (0.43) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL7816879 | 0.80 | GPR35 (0.50) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL9486017 | 0.78 | CYP2C19 (0.56) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL7817646 | 0.78 | GAA (0.39) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL7826454 | 0.77 | GPR35 (0.44) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL7826452 | 0.77 | GPR35 (0.44) | ALDH1A1L3MBTL1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-B1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5858995-A | ADMINISTERING TO HUMANS AND ANIMALS IN THE TREATMENT OF DISEASES CAUSED BY ABNORMAL BONE METABOLISM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| WO-1995029907-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-09 | — | — | WO | disclosed |