Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 3/20 | 0.33 |
| ▸ | BACE1 | P56817 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560802 | 0.80 | TRPV1 (0.51) | TRPV1CTSDBACE1 | |
| SCHEMBL6559512 | 0.78 | TRPV1 (0.52) | TRPV1 | |
| SCHEMBL11271692 | 0.67 | KMT2A (0.49) | TRPV1KMT2ACTSDBACE1 | |
| SCHEMBL6559509 | 0.66 | TRPV1 (0.45) | TRPV1KMT2A | |
| SCHEMBL11243410 | 0.65 | KMT2A (0.52) | TRPV1KMT2ACTSDBACE1 | |
| SCHEMBL11249928 | 0.64 | TRPV1 (0.44) | TRPV1KMT2ACTSDBACE1OPRL1 | |
| SCHEMBL11244401 | 0.64 | KMT2A (0.45) | TRPV1KMT2ACTSDBACE1 | |
| SCHEMBL11259857 | 0.63 | KMT2A (0.50) | TRPV1KMT2ACTSDBACE1 | |
| SCHEMBL11242102 | 0.63 | KMT2A (0.47) | TRPV1KMT2ACTSDBACE1 | |
| SCHEMBL11246466 | 0.63 | TRPV1 (0.54) | TRPV1KMT2ACTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |