Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 15/20 | 0.51 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559512 | 0.99 | TRPV1 (0.52) | TRPV1KCNE1KCNQ1 | |
| SCHEMBL6559589 | 0.83 | TRPV1 (0.52) | TRPV1KCNE1KCNQ1 | |
| SCHEMBL7828797 | 0.80 | TRPV1 (0.46) | TRPV1CTSDBACE1 | |
| SCHEMBL6560981 | 0.76 | KCNE1 (0.54) | TRPV1KCNE1KCNQ1 | |
| SCHEMBL6559570 | 0.75 | KCNE1 (0.55) | TRPV1KCNE1KCNQ1 | |
| SCHEMBL6559963 | 0.73 | TRPV1 (0.42) | TRPV1CTSDBACE1 | |
| Hydrochloric Acid SCHEMBL6559908 | 0.71 | TRPV1 (0.39) | TRPV1 | |
| SCHEMBL23408936 | 0.71 | TRPV1 (0.45) | TRPV1KCNE1KCNQ1 | |
| SCHEMBL6558641 | 0.70 | TRPV1 (0.39) | TRPV1CTSDBACE1 | |
| Hydrochloric Acid SCHEMBL6558690 | 0.70 | TRPV1 (0.40) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |