Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BMP1 | P13497 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828871 | 1.00 | LMNA (0.36) | LMNARECQLBMP1POLBGAA | |
| SCHEMBL7841906 | 0.91 | RECQL (0.38) | LMNARECQLBMP1POLBGAA | |
| SCHEMBL7841903 | 0.91 | RECQL (0.38) | LMNARECQLBMP1POLBGAA | |
| SCHEMBL7828980 | 0.85 | RECQL (0.35) | LMNARECQLBMP1POLBGAA | |
| SCHEMBL8196105 | 0.85 | RECQL (0.38) | LMNARECQLBMP1POLBGAA | |
| SCHEMBL8196106 | 0.85 | RECQL (0.38) | LMNARECQLBMP1POLBGAA | |
| SCHEMBL7836447 | 0.84 | LMNA (0.35) | LMNARECQLBMP1POLBGAA | |
| SCHEMBL7836444 | 0.84 | LMNA (0.35) | LMNARECQLBMP1POLBGAA | |
| SCHEMBL7840613 | 0.84 | RECQL (0.37) | LMNARECQLBMP1POLBGAA | |
| SCHEMBL7840615 | 0.84 | RECQL (0.37) | LMNARECQLBMP1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471372-B1 | Novel substituted guanidine derivatives, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-5256679-A | Pesticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| EP-0471372-A1 | Novel substituted guanidine derivatives, their preparation and use | Takeda Chemical Industries, Ltd. (JP) | 1992-02-19 | — | — | EP | disclosed |