Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.74 |
| ▸ | PPARG | P37231 | 2/20 | 0.74 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.74 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.74 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.74 |
| ▸ | ALB | P02768 | 1/20 | 0.74 |
| ▸ | HTR2C | P28335 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.69 |
| ▸ | ABCC4 | O15439 | 3/20 | 0.69 |
| ▸ | CNR1 | P21554 | 1/20 | 0.69 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.69 |
| ▸ | APEX1 | P27695 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27288111 | 1.00 | NR1I2 (0.74) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL7809090 | 1.00 | NR1I2 (0.74) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL8865962 | 0.93 | NR1I2 (0.85) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL10764553 | 0.93 | NR1I2 (0.85) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL8865950 | 0.93 | NR1I2 (0.85) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL10764568 | 0.93 | NR1I2 (0.85) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL10782284 | 0.93 | NR1I2 (0.85) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL9660055 | 0.91 | NR1I2 (0.88) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL11256358 | 0.91 | NR1I2 (0.88) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL9660046 | 0.91 | NR1I2 (0.88) | NR1I2MAPTPPARGSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074553-A1 | 7-Acyl-3-(substituted carbamoyloxy) cephem compounds, use thereof and process for their preparation | Eisai Co., Ltd. (JP) | 2001-02-07 | — | — | EP | disclosed |
| EP-0761671-A1 | Cephem derivatives | Eisai Co., Ltd. (JP) | 1997-03-12 | — | — | EP | disclosed |
| US-5604217-A | CEPHALOSPORIN ANTIBIOTICS | EISAI CO., LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| US-5587473-A | BLOCKING; CONDENSATION; DEBLOCKING | EISAI CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5563265-A | BACTERICIDES | EISAI CO., LTD. (JP) | 1996-10-08 | — | — | US | disclosed |
| US-5559225-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0484966-A2 | 7-Acyl-3-(substituted carbamoyloxy) cephem compounds, use thereof and process for their preparation | Eisai Co., Ltd. (JP) | 1992-05-13 | — | — | EP | disclosed |