Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 7/20 | 0.88 |
| ▸ | MAPT | P10636 | 3/20 | 0.88 |
| ▸ | PPARG | P37231 | 2/20 | 0.88 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.88 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.88 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.88 |
| ▸ | ALB | P02768 | 1/20 | 0.88 |
| ▸ | HTR2C | P28335 | 1/20 | 0.87 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.76 |
| ▸ | APEX1 | P27695 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.76 |
| ▸ | PKM | P14618 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | RECQL | P46063 | 1/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660046 | 1.00 | NR1I2 (0.88) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL9660055 | 1.00 | NR1I2 (0.88) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL11663869 | 0.99 | NR1I2 (0.87) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| Cefotaxime SCHEMBL5441795 | 0.94 | NR1I2 (1.00) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| Cefotaxime SCHEMBL3731937 | 0.94 | NR1I2 (1.00) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| Cefotaxime SCHEMBL9395572 | 0.94 | NR1I2 (1.00) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| Cefotaxime SCHEMBL15410 | 0.94 | NR1I2 (1.00) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| Cefotaxime SCHEMBL17422140 | 0.94 | NR1I2 (1.00) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| Cefotaxime SCHEMBL10748430 | 0.94 | NR1I2 (1.00) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| Cefotaxime SCHEMBL14594281 | 0.94 | NR1I2 (1.00) | NR1I2MAPTPPARGSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002586-B1 | METHOD FOR REMOVING A HALOGENOACETYL PROTECTIVE GROUP FROM A HALOGENOACETYL AMINO COMPOUND | Takeda Chemical Industries, Ltd. (JP) | 1982-01-20 | — | — | EP | disclosed |
| US-4251657-A | Method for removing protective groups | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-02-17 | — | — | US | disclosed |
| EP-0002586-A1 | Method for removing a halogenoacetyl protective group from a halogenoacetyl amino compound | Takeda Chemical Industries, Ltd. (JP) | 1979-06-27 | — | — | EP | disclosed |