SCHEMBL7828992

SCHEMBL7828992

N#CCC[N]CCCS(=O)(=O)CCCl

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
NLRP3 Q96P20 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7842552 0.89 CYP3A4 (0.36) CYP3A4TSHRNLRP3
SCHEMBL7804899 0.84
SCHEMBL8082142 0.78 CA2 (0.31)
SCHEMBL7840049 0.76 CA2 (0.39) TSHR
SCHEMBL9083510 0.76 CA2 (0.35) TSHR
SCHEMBL9082183 0.75
SCHEMBL7842591 0.73
SCHEMBL8067700 0.72
SCHEMBL7842074 0.71 CYP3A4 (0.33) CYP3A4TSHRNLRP3
SCHEMBL8706980 0.71 APEX1 (0.43) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0675172-B1 Water-solable azo compounds, process for their preparation and their use as dyestuffs DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-04-11 EP disclosed
US-5770709-A BRILLIANT COLOR SHADES, GOOD FASTNESS DURING USE AT HIGH DEGREE OF FIXING DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) 1998-06-23 US disclosed
US-5539088-A PROVIDE DYEINGS IN BRILLIANT SHADES WITH GOOD FASTNESS PROPERTIES AND HIGH DEGREE OF FIXATION HOECHST AKTIENGESELLSCHAFT (DE) 1996-07-23 US disclosed
EP-0675172-A2 Water-solable azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-04 EP disclosed
US-5393884-A Water soluble blue dyes HOECHST CELANESE CORPORATION (US) 1995-02-28 US disclosed
EP-0629667-A1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1994-12-21 EP disclosed
US-5302708-A Colorfastness HOECHST AKTIENGESELLSCHAFT (DE) 1994-04-12 US disclosed
US-5280110-A Fiber-reactive dye HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-18 US disclosed
EP-0471702-B1 WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE HOECHST AG (DE) 1993-12-29 EP disclosed
US-5256776-A Brilliant green dyeings; fiber reactive HOECHST AKTIENGESELLSCHAFT (DE) 1993-10-26 US disclosed
US-5227475-A WATER-SOLUBLE FIBER-REACTIVE DYESTUFFS CONTAINING A CYANAMIDO-SUBSTITUTED TRIAZINYLAMINO-GROUPING, AND A PROCESS FOR DYEING WITH THE USE OF THESE DYES HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-13 US disclosed
EP-0548792-A2 Water-soluble reactive dyes, their manufacture and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-30 EP disclosed
EP-0538785-A2 Water-soluble fiber-reactive dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-04-28 EP disclosed
EP-0530660-A2 Water-soluble phthalocyanine dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1993-03-10 EP disclosed
WO-1990013604-A1 WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-15 WO disclosed