Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | MMP2 | P08253 | 3/20 | 0.50 |
| ▸ | MMP9 | P14780 | 3/20 | 0.50 |
| ▸ | MMP12 | P39900 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27971821 | 0.86 | CYP2C9 (0.72) | SLC6A4CYP2C9CYP2C19HPGDLMNA | |
| SCHEMBL13241649 | 0.82 | SLC6A4 (0.68) | SLC6A4CYP2C9CYP2C19HPGDLMNA | |
| Chlorobenzene SCHEMBL28322357 | 0.79 | MAPT (0.43) | CYP2C9CYP2C19HPGDLMNAALDH1A1 | |
| SCHEMBL1191610 | 0.78 | SLC6A4 (0.63) | SLC6A4CYP2C9CYP2C19HPGDLMNA | |
| SCHEMBL6761043 | 0.77 | SLC6A4 (0.54) | SLC6A4CYP2C9CYP2C19HPGDLMNA | |
| SCHEMBL28549256 | 0.76 | L3MBTL1 (0.45) | CYP2C9CYP2C19HPGDLMNAMMP2 | |
| SCHEMBL11705626 | 0.76 | SLC6A4 (0.65) | SLC6A4CYP2C9CYP2C19HPGDLMNA | |
| SCHEMBL6763802 | 0.76 | SLC6A4 (0.52) | SLC6A4CYP2C9CYP2C19HPGDLMNA | |
| SCHEMBL2306567 | 0.76 | CHRM2 (0.54) | SLC6A4HPGDLMNAALDH1A1BLM | |
| SCHEMBL1191221 | 0.75 | SLC6A4 (0.63) | SLC6A4CYP2C9CYP2C19HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077927-A1 | NOVEL SUBSTITUTED CYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058495-A1 | NOVEL SUBSTITUTED CYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1999-11-18 | — | — | WO | disclosed |