Sulfuric Acid

Sulfuric Acid

SCHEMBL969448

Nc1ccc([N+](=O)[O-])cc1N.O=S(=O)(O)O

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.63
THRB P10828 1/20 0.63
CYP3A4 P08684 3/20 0.58
TSHR P16473 1/20 0.58
TDP1 Q9NUW8 5/20 0.58
ALDH1A1 P00352 4/20 0.58
ALOX15 P16050 1/20 0.58
MEN1 O00255 4/20 0.55
MAPT P10636 4/20 0.55
KMT2A Q03164 4/20 0.55
KDM4E B2RXH2 3/20 0.55
PKM P14618 1/20 0.55
RAB9A P51151 1/20 0.55
GPR35 Q9HC97 1/20 0.52
HTT P42858 1/20 0.50
NT5E P21589 1/20 0.50
GFER P55789 2/20 0.49
ATM Q13315 1/20 0.49
CA2 P00918 2/20 0.48
CA5A P35218 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL30000516 1.00 GAA (0.63) GAATHRBCYP3A4TSHRTDP1
SCHEMBL29353815 0.89 CYP3A4 (0.69) GAATHRBCYP3A4TSHRTDP1
SCHEMBL78293 0.89 CYP3A4 (0.69) GAATHRBCYP3A4TSHRTDP1
Methane SCHEMBL28785435 0.87 CYP3A4 (0.67) GAATHRBCYP3A4TSHRTDP1
Hydrochloric Acid SCHEMBL970606 0.87 CYP3A4 (0.67) GAATHRBCYP3A4TSHRTDP1
SCHEMBL31435677 0.87 CYP3A4 (0.67) GAATHRBCYP3A4TSHRTDP1
Hydrochloric Acid SCHEMBL970605 0.87 CYP3A4 (0.67) GAATHRBCYP3A4TSHRTDP1
2-Amino-4-Nitrophenol SCHEMBL3337658 0.87 GAA (0.86) GAATHRBCYP3A4TSHRTDP1
Sulfuric Acid SCHEMBL1881177 0.85 GAA (0.65) GAATHRBCYP3A4TSHRTDP1
Sulfuric Acid SCHEMBL28151771 0.85 TDP1 (0.81) GAATHRBCYP3A4TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110020251-A1 Ultraviolet-Absorbing Compounds AVOCA LLC 2011-01-27 US claimed
US-12583876-B2 Branched organosilicon compound, method of preparing same, and related compositions DOW SILICONES CORPORATION (US) 2026-03-24 US disclosed
EP-3493878-B1 COSMETIC COMPOSITION COMPRISING CURED SILICONE MATERIALS DOW SILICONES CORP (US) 2025-10-08 EP disclosed
US-12398270-B2 Acrylate-functional branched organosilicon compound, method of preparing same, and copolymer formed therewith DOW SILICONES CORPORATION (US) 2025-08-26 US disclosed
US-12371535-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith DOW SILICONES CORPORATION (US) 2025-07-29 US disclosed
US-12338259-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith DOW SILICONES CORPORATION (US) 2025-06-24 US disclosed
US-12269833-B2 Branched organosilicon compound, method of preparing same, and compositions comprising same DOW SILICONES CORPORATION (US) 2025-04-08 US disclosed
CN-119700592-A A hair-washing and caring composition capable of safely dyeing hair and relieving scalp irritation 广州旭妆生物科技有限公司 2025-03-28 CN disclosed
US-12215198-B2 Branched organosilicon compound, method of preparing same, and compositions comprising same DOW SILICONES CORPORATION (US) 2025-02-04 US disclosed
US-20240245600-A1 ORRIS ROOT EXTRACTS, COMPOSITIONS, AND METHODS FOR SKIN APPLICATIONS ACCESS BUSINESS GROUP INT LLC (US) 2024-07-25 US disclosed
EP-0716846-A1 Oxidation hair dye composition Yamahatsu Sangyo Kaisha Ltd. (JP) 1996-06-19 EP disclosed
EP-0410471-B1 2-alkyl-4-methoxy-5-aminophenol or salt thereof, or 2-alkyl-4-methoxy-5-substituted aminophenol or salt thereof, and dyeing composition for keratin fibers comprising the same KAO CORP (JP) 1995-05-17 EP disclosed
US-5334225-A Imparts color tone of high chroma; excellent in coloring power and fastness KAO CORPORATION (JP) 1994-08-02 US disclosed
EP-0435012-B1 2-part hair dyeing agent SUNSTAR KK (JP) 1994-04-27 EP disclosed
EP-0579204-A2 Dye composition for a keratinous fiber KAO CORPORATION (JP) 1994-01-19 EP disclosed
US-5131912-A Compound capable of forming bicarbonate by dissociation in water, alkali generating no irritating odor, hydrogen peroxide, buffer solution; ph control SUNSTAR KABUSHIKI KAISHA (JP) 1992-07-21 US disclosed
US-5104414-A 2-alkyl-4-methoxy-5-aminophenol or salt thereof, or 2-alkyl-4-methoxy-5-substituted aminophenol or salt thereof, and dyeing composition for keratin fibers comprising the same KAO CORPORATION (JP) 1992-04-14 US disclosed
EP-0435012-A1 2-part hair dyeing agent SUNSTAR KABUSHIKI KAISHA (JP) 1991-07-03 EP disclosed
US-5015260-A Hair dyes for reaction with developer KAO CORPORATION (JP) 1991-05-14 US disclosed
EP-0410471-A2 2-alkyl-4-methoxy-5-aminophenol or salt thereof, or 2-alkyl-4-methoxy-5-substituted aminophenol or salt thereof, and dyeing composition for keratin fibers comprising the same Kao Corporation (JP) 1991-01-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12215198-B2 Branched organosilicon compound, method of preparing same, and compositions comprising same ORC3, OXSR1, OR10J3 GAA 4594/4885THRB 2190/4885CYP3A4 1394/4885
US-20110020251-A1 Ultraviolet-Absorbing Compounds UFM1, UHRF1, CUTA GAA 4597/4885THRB 3491/4885CYP3A4 2797/4885
US-12583876-B2 Branched organosilicon compound, method of preparing same, and related compositions OXSR1, BRS3, NPSR1 GAA 4501/4885THRB 696/4885CYP3A4 931/4885
US-12269833-B2 Branched organosilicon compound, method of preparing same, and compositions comprising same NR3C2, NR2E3, OXER1 GAA 4768/4885THRB 831/4885CYP3A4 1926/4885
US-12338259-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith OXSR1, BRS3, ORC3 GAA 3655/4885THRB 1710/4885CYP3A4 1716/4885
US-12371535-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith OXSR1, BRS3, OXER1 GAA 4550/4885THRB 603/4885CYP3A4 1178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.