SCHEMBL78298

SCHEMBL78298

C1=C[N]NC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1397373 0.67
SCHEMBL10009143 0.55
SCHEMBL1149540 0.55
SCHEMBL221803 0.55
SCHEMBL17203678 0.55
Hydrochloric Acid SCHEMBL31261787 0.54
SCHEMBL31540574 0.54
Pyridazine SCHEMBL449549 0.47
SCHEMBL2384 0.47
SCHEMBL6276848 0.45

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1306 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024115549-A1 ARYL- AND HETEROARYL-SULFONAMIDE DERIVATIVES AS CCR8 MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2024-06-06 WO claimed
CN-118139837-A Stilbene derivative, preparation method and application thereof 上海泽德曼医药科技有限公司 2024-06-04 CN claimed
CN-112888696-B Exonuclease inhibitors and methods of use thereof 德琪医疗有限公司 2024-04-16 CN claimed
WO-2024061187-A1 STILBENE DERIVATIVES AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF 上海泽德曼医药科技有限公司 2024-03-28 WO claimed
US-20240043435-A1 TYK-2 INHIBITOR BEONE MEDICINES I GMBH (CH) 2024-02-08 US claimed
US-20230338429-A1 COMPOUNDS AND USE THEREOF IN THE EXPANSION OF STEM CELLS AND/OR PROGENITOR CELLS UNIVERSITE DE MONTREAL (CA) 2023-10-26 US claimed
EP-4168398-A1 TYK-2 INHIBITOR BeiGene, Ltd. (KY) 2023-04-26 EP claimed
WO-2023025783-A1 SMALL MOLECULE MODULATORS OF IL-17 LEO PHARMA A/S (DK) 2023-03-02 WO claimed
CN-115715288-A TYK-2 inhibitors 百济神州有限公司 2023-02-24 CN claimed
CN-114901284-A Methods of treating cancer in patients identified by biomarkers with cyclin dependent kinase 7(CDK7) inhibitors 希洛斯医药品股份有限公司 2022-08-12 CN claimed
CN-1061966-A Contain herbicidal composition of uracil derivative and preparation method thereof NISSAN CHEMICAL IND LTD (JP) 1992-06-17 CN claimed
WO-1991006542-A1 PHARMACEUTICALLY ACTIVE AMINO-SUBSTITUTED HETEROARYL AMINES THE UPJOHN COMPANY (US) 1991-05-16 WO claimed
CN-1046903-A Process for preparing heterocyclic ether derivatives ICI PLC (GB) 1990-11-14 CN claimed
EP-0396282-A2 N-aryl-N-[4-(heterocyclicalkyl) piperidinyl]amides and pharmaceutical compositions and methods employing such compounds BOC, INC. (US) 1990-11-07 EP claimed
EP-0306148-A2 Azabicyclic ethers JOHN WYETH &amp; BROTHER LIMITED (GB) 1989-03-08 EP claimed
CN-1031532-A HETEROCYCLIC COMPOUNDS WELLCOME FOUND (GB) 1989-03-08 CN claimed
EP-0055583-B1 ANTIHYPERTENSIVES Pfizer Limited (GB) 1985-08-28 EP claimed
US-4439225-A Herbicidal cyano-tetrahydrofuranylmethyl ether and cyano-tetrahydropyranylmethyl ether derivatives SHELL OIL COMPANY (US) 1984-03-27 US claimed
US-4419363-A ADRENERGIC BLOCKING AGENTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-12-06 US claimed
US-4273782-A FOR USE IN CARDIOVASCULAR DISORDERS AND COMPLICATIONS OF DIABETES PFIZER INC. (US) 1981-06-16 US claimed