SCHEMBL7829810

SCHEMBL7829810

CCCOC1(OC)NC(=N)c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.33
MDM2 Q00987 2/20 0.33
CYP2C9 P11712 2/20 0.32
CYP2C19 P33261 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
PDK2 Q15119 1/20 0.32
MEN1 O00255 1/20 0.31
RECQL P46063 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7825080 0.92 CYP2C9 (0.34) TP53MDM2CYP2C9CYP2C19NPSR1
SCHEMBL7828902 0.92 CYP2C9 (0.41) CYP2C9CYP2C19NPSR1PDK2MEN1
SCHEMBL7816154 0.90 NPSR1 (0.41) TP53CYP2C9CYP2C19NPSR1PDK2
SCHEMBL7823192 0.89 NPSR1 (0.43) TP53CYP2C9CYP2C19NPSR1PDK2
SCHEMBL7828086 0.89 NPSR1 (0.43) TP53CYP2C9CYP2C19NPSR1PDK2
SCHEMBL7817466 0.89 NPSR1 (0.43) TP53CYP2C9CYP2C19NPSR1PDK2
SCHEMBL7826241 0.88 SMN1; SMN2 (0.35) TP53MDM2CYP2C9CYP2C19NPSR1
SCHEMBL7829061 0.88 SMN1; SMN2 (0.36) PDK2MEN1KMT2AALDH1A1
SCHEMBL7826997 0.87 CYP2C9 (0.42) TP53MDM2CYP2C9CYP2C19NPSR1
SCHEMBL3129229 0.86 ALDH1A1 (0.34) TP53CYP2C9CYP2C19PDK2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679640-B1 Carboxylate and heat-sensitive recording material using same MITSUI CHEMICALS INC (JP) 2001-08-08 EP disclosed
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
CN-1114431-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS (JP) 1996-01-03 CN disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed