Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.57 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 6/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 9/20 | 0.42 |
| ▸ | NPC1 | O15118 | 7/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829827 | 1.00 | MAPT (0.57) | MAPTNOX1MEN1KMT2APOLB | |
| SCHEMBL7483622 | 0.91 | MEN1 (0.49) | MAPTNOX1MEN1KMT2APOLB | |
| SCHEMBL7483627 | 0.91 | MEN1 (0.49) | MAPTNOX1MEN1KMT2APOLB | |
| SCHEMBL7843648 | 0.84 | LMNA (0.46) | MAPTNOX1MEN1KMT2APOLB | |
| SCHEMBL7843652 | 0.84 | LMNA (0.46) | MAPTNOX1MEN1KMT2APOLB | |
| SCHEMBL7990285 | 0.83 | MEN1 (0.44) | MAPTMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL7990282 | 0.83 | MEN1 (0.44) | MAPTMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL8005181 | 0.80 | KMT2A (0.39) | MAPTMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL8005183 | 0.80 | KMT2A (0.39) | MAPTMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL8002204 | 0.78 | NPC1 (0.40) | MAPTMEN1KMT2APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737672-B1 | Method of producing triazine derivatives | TAKEDA SCHERING PLOUGH ANIMAL (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-6211178-B1 | ANTIPROTOZOA AGENTS FOR COCCIDIOIDES; CYCLIZATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| US-5994355-A | ANTIPROTOZOA AGENTS, PARASITICIDE; VETERINARY MEDICINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0737672-A2 | Method of producing triazine derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-16 | — | — | EP | disclosed |