Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | CDC25B | P30305 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | APAF1 | O14727 | 2/20 | 0.44 |
| ▸ | TDP2 | O95551 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22930024 | 0.81 | L3MBTL1 (0.38) | MEN1KMT2AMAPK1RAB9AMAPT | |
| SCHEMBL8546620 | 0.76 | MEN1 (0.32) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL4624211 | 0.72 | CDC25B (0.50) | MEN1KMT2ACDC25BMAPK1RAB9A | |
| Anthraquinone SCHEMBL29358690 | 0.72 | MEN1 (1.00) | MEN1KMT2ACDC25BMAPK1RAB9A | |
| Anthraquinone SCHEMBL1901249 | 0.72 | MEN1 (1.00) | MEN1KMT2ACDC25BMAPK1RAB9A | |
| Anthraquinone SCHEMBL14943 | 0.72 | MEN1 (1.00) | MEN1KMT2ACDC25BMAPK1RAB9A | |
| Anthraquinone SCHEMBL5082838 | 0.71 | MEN1 (0.71) | MEN1KMT2ACDC25BMAPK1RAB9A | |
| Anthraquinone SCHEMBL7205968 | 0.69 | MEN1 (0.92) | MEN1KMT2ACDC25BMAPK1RAB9A | |
| Anthraquinone SCHEMBL6415478 | 0.69 | MEN1 (0.92) | MEN1KMT2ACDC25BMAPK1RAB9A | |
| Anthraquinone SCHEMBL20299926 | 0.69 | MEN1 (0.92) | MEN1KMT2ACDC25BMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750619-B1 | HETERO-ANNULATED INDAZOLES | NOVUSPHARMA SPA (IT) | 2001-05-30 | — | — | EP | disclosed |
| US-5596097-A | ANTITUMOR AGENTS | THE UNIVERSITY OF VERMONT (US) | 1997-01-21 | — | — | US | disclosed |
| EP-0750619-A1 | HETERO-ANNULATED INDAZOLES | BOEHRINGER MANNHEIM ITALIA S.p.A. (IT) | 1997-01-02 | — | — | EP | disclosed |
| WO-1995024407-A1 | HETERO-ANNULATED INDAZOLES | BOEHRINGER MANNHEIM ITALIA, S.P.A. (IT) | 1995-09-14 | — | — | WO | disclosed |