Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 7/20 | 0.85 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.85 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.85 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.85 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.85 |
| ▸ | G6PD | P11413 | 6/20 | 0.66 |
| ▸ | GABRP | O00591 | 2/20 | 0.66 |
| ▸ | GABRD | O14764 | 2/20 | 0.66 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.66 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.66 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.66 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.66 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.66 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.66 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.66 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.66 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.66 |
| ▸ | GABRE | P78334 | 2/20 | 0.66 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.66 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL783064 | 0.92 | GRIN1 (1.00) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL19281748 | 0.92 | GRIN1 (1.00) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL782132 | 0.92 | GRIN1 (1.00) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL782131 | 0.92 | GRIN1 (1.00) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL4191973 | 0.92 | GRIN1 (1.00) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL24703701 | 0.92 | GRIN1 (1.00) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL8075513 | 0.92 | GRIN1 (1.00) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL6377561 | 0.92 | GRIN1 (1.00) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL4198024 | 0.92 | GRIN1 (1.00) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL19253173 | 0.89 | GRIN1 (0.85) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3243829-A1 | STEROID ANIONIC COMPOUNDS, METHOD FOR THEIR PRODUCTION, USE AND PHARMACEUTICAL PREPARATION CONTAINING THEM | Ústav Organické Chemie A Biochemie Akademie Ved Ceské Republiky, v.v.i. (CZ) | 2017-11-15 | — | — | EP | disclosed |
| EP-2435463-B1 | STEROIDE ANIONIC COMPOUNDS, METHOD OF THEIR PRODUCTION, USAGE AND PHARMACEUTICAL PREPARATION INVOLVING THEM | ÚSTAV ORGANICKÉ CHEMIE BIOCHEMIE AKADEMIE VED CESKÉ REPUBLIKY V V I (CZ) | 2016-10-12 | — | — | EP | disclosed |
| EP-2313424-B1 | ANIONIC PREGNANE COMPOUNDS, METHOD FOR THEIR PRODUCING AND USE OF THEM | USTAV ORGANICKE CHEMIE A BIOCHEMIE AKADEMIE VED CESKE REPUBLIKY V V I (CZ) | 2014-04-23 | — | — | EP | disclosed |
| US-8575376-B2 | Steroide anionic compounds, method of their production, usage and pharmaceutical preparation involving them | USTAV ORGANICKE CHEMIE A BIOCHEMIE AKADEMIE VED CESKE REPUBLIKY, V.V.I. (CZ) | 2013-11-05 | — | — | US | disclosed |
| EP-2435463-A2 | STEROIDE ANIONIC COMPOUNDS, METHOD OF THEIR PRODUCTION, USAGE AND PHARMACEUTICAL PREPARATION INVOLVING THEM | Ustav Organicke Chemie A Biochemie Akademie Ved Ceske Republiky (CZ) | 2012-04-04 | — | — | EP | disclosed |
| US-20120071453-A1 | STEROIDE ANIONIC COMPOUNDS, METHOD OF THEIR PRODUCTION, USAGE AND PHARMACEUTICAL PREPARATION INVOLVING THEM | PSYCHIATRICKE CENTRUM PRAHA (CZ) | 2012-03-22 | — | — | US | disclosed |
| EP-2313424-A2 | ANIONIC PREGNANE COMPOUNDS, METHOD FOR THEIR PRODUCING AND USE OF THEM | Ustav Organicke Chemie A Biochemie Akademie Ved Ceske Republiky (CZ) | 2011-04-27 | — | — | EP | disclosed |
| WO-2010136000-A2 | STEROIDE ANIONIC COMPOUNDS, METHOD OF THEIR PRODUCTION, USAGE AND PHARMACEUTICAL PREPARATION INVOLVING THEM | ÚSTAV ORGANICKÉ CHEMIE BIOCHEMIE AKADEMIE VĚD ČESKÉ REPUBLIKY, V.V.I. (CZ) | 2010-12-02 | — | — | WO | disclosed |
| WO-2010003391-A2 | ANIONIC PREGNANE COMPOUNDS, METHOD FOR THEIR PRODUCING AND USE OF THEM | USTAV ORSANICKE CHEMIE A BIOCHEMIE AKADEMIE VED CESKE REPUBLIKY, V.V.I. (CZ) | 2010-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071453-A1 | STEROIDE ANIONIC COMPOUNDS, METHOD OF THEIR PRODUCTION, USAGE AND PHARMACEUTICAL PREPARATION INVOLVING THEM | GRIN2A, GRIN2B, GRIN1 | GRIN1 3/4885GRIN2B 2/4885GRIN2D 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.