Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | CALML3 | P27482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SDHA | P31040 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 7/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831660 | 0.92 | CALML3 (0.51) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL1498789 | 0.90 | MAOB (0.53) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL5417793 | 0.90 | MAOB (0.53) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL7830667 | 0.88 | MAOB (0.42) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL7833227 | 0.88 | MAOA (0.61) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL6397617 | 0.86 | CALML3 (0.45) | MAOBMAOACALML3F10 | |
| SCHEMBL27364293 | 0.86 | CALML3 (0.45) | MAOBMAOACALML3F10 | |
| SCHEMBL13367771 | 0.83 | F10 (0.45) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL5327254 | 0.82 | MAOB (0.53) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL1498683 | 0.82 | MAOB (0.53) | MAOBMAOACALML3LMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828741-B1 | SPIROCYCLIC AND BICYCLIC DIAZINYL AND CARBAZINYL OXAZOLIDINONES | UPJOHN CO (US) | 2001-08-29 | — | — | EP | disclosed |
| US-6090820-A | MICROBIOCIDES, BATERICIDES | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-18 | — | — | US | disclosed |
| EP-0828741-A1 | SPIROCYCLIC AND BICYCLIC DIAZINYL AND CARBAZINYL OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996035691-A1 | SPIROCYCLIC AND BICYCLIC DIAZINYL AND CARBAZINYL OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 1996-11-14 | — | — | WO | disclosed |