Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 7/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7830734 | 0.88 | SLC9A1 (0.45) | SLC9A1BACE1 | |
| SCHEMBL9392176 | 0.85 | GAA (0.44) | SLC9A1BACE1ASIC3PARP10 | |
| SCHEMBL7824223 | 0.83 | SLC9A1 (0.42) | SLC9A1 | |
| SCHEMBL7822636 | 0.81 | SLC9A1 (0.40) | SLC9A1 | |
| SCHEMBL27469085 | 0.78 | SLC9A1 (0.53) | SLC9A1 | |
| SCHEMBL7826584 | 0.78 | SLC9A1 (0.53) | SLC9A1 | |
| SCHEMBL7824218 | 0.73 | SLC9A1 (0.49) | SLC9A1 | |
| Hydrochloric Acid SCHEMBL8896537 | 0.73 | SLC9A1 (0.44) | SLC9A1 | |
| SCHEMBL7822631 | 0.73 | SLC9A1 (0.48) | SLC9A1 | |
| Guanidine SCHEMBL8703094 | 0.73 | GAA (0.40) | PARP10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699185-B1 | GUANIDINE DERIVATIVES AS INHIBITORS OF Na+ /H+ EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-0699185-A1 | GUANIDINE DERIVATIVES AS INHIBITORS OF Na+ /H+ EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-03-06 | — | — | EP | disclosed |