Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 6/20 | 0.61 |
| ▸ | MAOA | P21397 | 12/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7830744 | 1.00 | CALML3 (0.61) | CALML3MAOAMAOBCYP3A4CYP2D6 | |
| SCHEMBL7829561 | 0.85 | MAOA (0.68) | CALML3MAOAMAOB | |
| SCHEMBL7829558 | 0.85 | MAOA (0.68) | CALML3MAOAMAOB | |
| SCHEMBL8111378 | 0.85 | CALML3 (0.61) | CALML3MAOAMAOBCYP3A4CYP2D6 | |
| SCHEMBL8111373 | 0.85 | CALML3 (0.61) | CALML3MAOAMAOBCYP3A4CYP2D6 | |
| SCHEMBL14540833 | 0.85 | MAOB (0.55) | CALML3MAOAMAOBCYP3A4CYP2D6 | |
| SCHEMBL14213964 | 0.84 | MAOA (0.54) | CALML3MAOAMAOBCYP3A4CYP2D6 | |
| SCHEMBL7840221 | 0.83 | MAOB (0.53) | CALML3MAOAMAOB | |
| SCHEMBL7840219 | 0.83 | MAOB (0.53) | CALML3MAOAMAOB | |
| SCHEMBL14852816 | 0.83 | MAOA (0.66) | CALML3MAOAMAOBCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1075073-C | Hetero-aromatic ring substituted phenyloxazolidinone antimicrobials | UPJOHN CO (US) | 2001-11-21 | — | — | CN | disclosed |
| EP-0807112-B1 | HETERO-AROMATIC RING SUBSTITUTED PHENYLOXAZOLIDINONE ANTIMICROBIALS | UPJOHN CO (US) | 2001-09-05 | — | — | EP | disclosed |
| US-6124334-A | A BACTERICIDE TREATING INFECTIONS CAUSED BY GRAM-POSITIVE AEROBIC BACTERIA SUCH AS STAPHYLOCOCCUS, STREPTOCOCCUS AND ENTEROCOCCUS AS WELL AS ANAEROBIC ORGANISMS SUCH AS BACTEROIDES AND CLOSTRIDIUM AND MYCOBACTERIDIUM | PHARMACIA & UPJOHN COMPANY (US) | 2000-09-26 | — | — | US | disclosed |
| US-5910504-A | BACTERICIDES TREATING INFECTIONS | PHARMACIA & UPJOHN (US) | 1999-06-08 | — | — | US | disclosed |
| CN-1172484-A | Phenyl oxazolidinone antibacterial agents substituted with heteroaromatic rings | UPJOHN CO (US) | 1998-02-04 | — | — | CN | disclosed |
| WO-1996023788-A1 | HETERO-AROMATIC RING SUBSTITUTED PHENYLOXAZOLIDINONE ANTIMICROBIALS | PHARMACIA + UPJOHN COMPANY (US) | 1996-08-08 | — | — | WO | disclosed |