SCHEMBL7831352

SCHEMBL7831352

NC1=NN(c2ccc(Oc3ccccc3)c(S(=O)(=O)O)c2)C(=O)C1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 5/20 0.56
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
L3MBTL1 Q9Y468 3/20 0.56
RXFP1 Q9HBX9 2/20 0.56
APEX1 P27695 1/20 0.56
SMN1; SMN2 Q16637 3/20 0.53
MAPT P10636 5/20 0.48
GAA P10253 3/20 0.48
ALDH1A1 P00352 4/20 0.48
KDM4E B2RXH2 3/20 0.48
ALOX15 P16050 2/20 0.48
DUSP3 P51452 1/20 0.48
PTPN5 P54829 1/20 0.48
PTPN11 Q06124 1/20 0.48
HSD17B10 Q99714 1/20 0.48
CTDSP1 Q9GZU7 1/20 0.48
TDP1 Q9NUW8 3/20 0.37
USP2 O75604 1/20 0.37
THRB P10828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30390032 0.99 POLB (0.55) POLBMEN1KMT2AL3MBTL1RXFP1
Ammonia Solution, Strong SCHEMBL5449039 0.99 POLB (0.55) POLBMEN1KMT2AL3MBTL1RXFP1
SCHEMBL29022580 0.99 POLB (0.55) POLBMEN1KMT2AL3MBTL1RXFP1
SCHEMBL5449043 0.88 MAPT (0.45) POLBMEN1KMT2AL3MBTL1RXFP1
SCHEMBL28753724 0.84 GAA (0.48) POLBMEN1KMT2AL3MBTL1RXFP1
SCHEMBL17817254 0.82 POLB (0.48) POLBMEN1KMT2AL3MBTL1RXFP1
SCHEMBL6720846 0.79 POLB (0.48) POLBMEN1KMT2AL3MBTL1RXFP1
SCHEMBL28753721 0.79 POLB (0.57) POLBMEN1KMT2AL3MBTL1RXFP1
SCHEMBL14429924 0.76 MAPT (0.48) POLBMEN1KMT2AL3MBTL1RXFP1
SCHEMBL14429913 0.76 MAPT (0.48) POLBMEN1KMT2AL3MBTL1RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119114152-A Free radical generating catalyst, method for producing free radical, method for producing oxidation reaction product, pharmaceutical agent, and agricultural and livestock pharmaceutical agent 株式会社ACENET 2024-12-13 CN disclosed
CN-118695780-A Composition and method for producing the same 阿斯制药株式会社 2024-09-24 CN disclosed
CN-110769931-B Free radical generating catalyst, method for producing free radical, method for producing oxidation reaction product, pharmaceutical agent, and agricultural and livestock pharmaceutical agent 株式会社ACENET 2024-09-17 CN disclosed
US-12036208-B2 Methods for treating neurodegenerative disorders ALZHEON, INC. (US) 2024-07-16 US disclosed
US-12036208-B2 Methods for treating neurodegenerative disorders ALZHEON, INC. (US) 2024-07-16 US disclosed
CN-117281115-A Free radical generating catalyst, method for producing free radical, method for producing oxidation reaction product, pharmaceutical agent, and agricultural and livestock pharmaceutical agent 株式会社ACENET 2023-12-26 CN disclosed
EP-4230042-A1 ANTIPATHOGENIC DRUG, ANTIBACTERIAL AGENT, ANTIVIRAL AGENT, PATHOGEN PROCESSING DEVICE, METHOD FOR PRODUCING ANTIPATHOGENIC DRUG, ANTIBACTERIAL METHOD, VIRUS INACTIVATION METHOD, AND PATHOGEN PROCESSING METHOD Acenet Inc. (JP) 2023-08-23 EP disclosed
CN-116322332-A Antipathogenic agent, antibacterial agent, antiviral agent, pathogen treatment device, method for producing antipathogenic agent, antibacterial method, virus inactivation method, and pathogen treatment method 株式会社ACENET 2023-06-23 CN disclosed
CN-116157109-A Oral pharmaceutical preparation 国立大学法人大阪大学 2023-05-23 CN disclosed
EP-4147703-A1 EPITHELIAL CANCER THERAPEUTIC AGENT OSAKA UNIVERSITY (JP) 2023-03-15 EP disclosed
WO-2022075451-A1 ANTIPATHOGENIC DRUG, ANTIBACTERIAL AGENT, ANTIVIRAL AGENT, PATHOGEN PROCESSING DEVICE, METHOD FOR PRODUCING ANTIPATHOGENIC DRUG, ANTIBACTERIAL METHOD, VIRUS INACTIVATION METHOD, AND PATHOGEN PROCESSING METHOD 株式会社エースネット 2022-04-14 WO disclosed
US-11077095-B2 Methods for treating neurodegenerative disorders ALZHEON, INC. (US) 2021-08-03 US disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11077095-B2 Methods for treating neurodegenerative disorders NLN, CLN6, SNCA POLB 2079/4885MEN1 4000/4885KMT2A 3467/4885
US-12036208-B2 Methods for treating neurodegenerative disorders NLN, CLN6, SNCA POLB 2079/4885MEN1 4000/4885KMT2A 3467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.