Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.66 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PRNP | P04156 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831718 | 1.00 | CYSLTR2 (0.66) | CYSLTR2CYSLTR1MEN1KMT2APRNP | |
| SCHEMBL7832861 | 0.82 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1MEN1KMT2APRNP | |
| SCHEMBL7832237 | 0.82 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1MEN1KMT2APRNP | |
| SCHEMBL7832243 | 0.82 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1MEN1KMT2APRNP | |
| SCHEMBL13783858 | 0.81 | HDAC1 (0.66) | CYSLTR2CYSLTR1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL711192 | 0.79 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 | |
| SCHEMBL711191 | 0.79 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 | |
| SCHEMBL22501441 | 0.79 | KDM4E (0.50) | CYSLTR2CYSLTR1MEN1KMT2AKDM4E | |
| SCHEMBL7832354 | 0.79 | HDAC1 (0.64) | KDM4ELMNAMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL7829154 | 0.79 | HDAC1 (0.64) | KDM4ELMNAMAPTSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737671-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-12 | — | — | EP | disclosed |
| EP-0737671-A2 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-10-16 | — | — | EP | disclosed |